Cardiovascular spasm causes narrowing of the lumen, myocardial ischemia as well as manifestations of angina pectoris, such as chest tightness, panic, and dyspnea. Cardiovascular spasm may be caused by physiological factors, such as cold, strenuous exercise. It may also be caused by diseases, drugs and other factors, patients need to go to the hospital, clear cause for treatment. 1. Physiological factors: when the patient is in a state of mental tension, suddenly stimulated, or in a cold state, will lead to strong contraction of the heart’s blood vessels, causing vasospasm. 2. Disease factors: damage to the endothelium of blood vessels can lead to vasoconstriction and spasm. 3. Drug factors: the wrong use of vasoconstrictor drugs, such as dobutamine, will lead to excessive vasoconstriction, thus causing abnormal spasms. Such cases need to go to the hospital in time to check the cause of the disease and follow the doctor’s instructions for treatment.