The quadruple medication is taken and then stopped for 1 month before checking again. Quadruplex is a quadruple therapy for H. pylori, such as omeprazole, bismuth potassium citrate, clarithromycin, and amoxicillin, which are proton pump inhibitors, gastric mucosal protectors, and antibiotics, respectively. Because antibiotics and proton pump inhibitors need to be discontinued for 1 month before the H. pylori detected will not be false negative, so go for a checkup 1 month after taking the quadruple. A review after 1 month of taking Quadruple can detect whether H. pylori has been eliminated by bacteriology and pathohistology. Of course, the most common and easiest test is the carbon 13 or carbon 14 breath test, which can determine whether H. pylori has been eradicated. Reviewing the test within 1 month after stopping the medication may give a false-negative result, which may affect the treatment. H. pylori testing should be done under a doctor’s supervision and medications should be taken as prescribed. ,,