The phenomenon of blisters on the genital root is commonly caused by infection with genital herpes virus, a disease transmitted through sexual contact, and the blisters contain a large number of viruses, so they are highly contagious. It appears one month after the occurrence of impure sexual intercourse, blisters appear on the root of the penis, above the scrotum, around the anus, etc., and there is a significant stinging pain, which is diagnosed by the genital herpes virus antibody test and promptly treated with antiviral therapy. It is also considered to be caused by skin inflammation or allergy at the root of the penis. If the inflammatory infection or allergy is more serious, symptoms such as blisters and ulcers may appear at the root of the genitalia, so promptly seek medical attention and further anti-infection or anti-allergy treatment under the guidance of a doctor. In addition, this blistering phenomenon should also be considered to be caused by a common viral infection, such as herpes zoster virus infection.