The choice of medication for forefoot pain should be based on the cause, with common causes including strain, incorrect posture, and poorly fitting shoes, as well as fasciitis, gout, and metatarsalgia. Medications for treatment include non-steroidal anti-inflammatory drugs and uric acid-lowering drugs. 1. For those caused by strain, pay attention to rest; for those caused by incorrect posture, pay attention to correcting bad posture; for those caused by inappropriate shoes, choose appropriate shoes. For those caused by fasciitis, gout and metatarsalgia, oral medication is needed. 2. Fasciitis: caused by long-term strain, oral non-steroidal anti-inflammatory drugs such as celecoxib etc. to relieve. 3. Gout: often caused by uric acid metabolism disorder, acute oral colchicine, benzbromarone and other drugs to relieve. 4. Metatarsalgia: caused by heavy pressure or extrusion, weight-bearing imbalance and overuse, etc. Acute oral non-steroidal anti-inflammatory drugs such as aspirin and other relief. There may be other causes of forefoot pain, such as bone fracture, etc. When forefoot pain occurs, it is important to go to the hospital at the first time, to make a clear diagnosis and then use the medication, the choice and use of drugs should be carried out under the guidance of the doctor.