Folic acid is recommended for both men and women during the preparation for pregnancy, and men should stop taking it when they become pregnant, while pregnant women should continue to take it until after the third trimester of pregnancy, depending on the actual need to determine whether to continue to take it. Folic acid is a drug that prevents neural tube malformations in the fetus, and also has the effect of preventing anemia. During the preparation for pregnancy, it is recommended that women should take it, and it is recommended that men can also take it at the same time, in the three months before the preparation for pregnancy, both husband and wife can take folic acid tablets together, three months after taking it to start the preparation for pregnancy, and in the three months after the pregnancy, women are taking it. During the preparation for pregnancy, it is necessary to eat more food rich in protein, such as eggs, pork lean meat, soy products, milk and so on. It is also necessary to properly supplement shrimp, fish, pork liver, oats, walnuts, peanuts and other foods, eat more fresh vegetables and fruits, to ensure that the intake of food nutritionally balanced, to avoid a single nutrition. Prepare for pregnancy before the couple had better go to the hospital to do eugenics examination, folic acid metabolism gene examination, under the guidance of the doctor to take the dose. Folic acid taking period, once there is any discomfort, need by the doctor according to the specific circumstances, the development of individualized diagnosis and treatment plan to adjust the medication.