Ichthyosarcoma on the hand is usually due to herpes caused by the disease, but also can not be ruled out due to HPV infection, it is recommended that the patient timely medical examination, and under the guidance of the doctor according to the actual situation to choose the appropriate treatment. 1. Herpes: mainly due to human herpes virus infection caused by skin diseases, clinical symptoms are mostly manifested as blisters, pain, etc., may also appear ichthyosarcoma, it is recommended to consult a doctor in time for examination, and under the guidance of the doctor according to the actual situation to choose glycerine lotion, acyclovir and other drugs for treatment. 2. HPV infection: it is usually caused by human papilloma virus infection, which belongs to infectious diseases. Once infected with HPV, patients may develop ichthyosarcoma if they are not treated in time. Patients can use take surgical excision, freezing, electrocautery and other methods of treatment under the guidance of the doctor according to the actual situation. Based on the symptom of ichthyosarcoma on the hand alone, it is not possible to accurately determine its cause, but also needs to be combined with the characteristics of the medical history, the relevant examination results in order to make an accurate judgment, it is recommended to clarify the cause of the disease under the guidance of a doctor.