Many TCM doctors are used to prescribing large prescriptions, with a few dozen drugs in the formula, more than a few dozen. When asked why, the answer is: the condition is complex, so they have to prescribe generously. It is true that a good Chinese medicine compound can achieve the purpose of reducing toxicity, increasing effectiveness and taking into account a variety of diseases. However, with the increase in the number of drugs in the formula, the following drawbacks often arise: 1. When there are more drugs in a formula, it is inevitable that they will react with each other, with both favorable and unfavorable reactions. Such as Chinese medicine with the seven emotions in the phase of evil and opposite. “The opposite is that the two drugs together can produce or enhance toxicity or side effects. Both of these situations need to be avoided as much as possible. At present, we have limited knowledge about the opposite of the evil and opposite. For example, the opposite content used in the textbook of traditional Chinese medicine is only 18 anti and 19 aversions, while the opposite recorded in the literature of herbal medicine in the past generations is more than these two, and the recorded opposite evils are countless. For example, the “Compendium of Materia Medica”: “Euphorbia anti-coriander, seaweed.” “Xuan ginseng evil astragalus, ginger, jujube, cornelian.” These are documented to be evil, opposite has not been thoroughly studied, so it is not appropriate to easily deny. In addition, limited by the historical limitations of human understanding, there may be other phases of evil and opposite that we have not yet perceived. It is inevitable that these various kinds of phase evils and contraries will occur in compound prescriptions, and as the number of drugs in a prescription increases, the probability of phase evils and contraries occurring will greatly increase, thus affecting the efficacy of the medicine. In addition, we can also get the opposite evidence in the application of “single line” of Chinese medicine. The purpose of applying a single medicine is to make it more effective and powerful for emergency use. The “Collected Notes on the Materia Medica” has a single line of path to use to the urgent elaboration. For example, in “The Divine Book of Ten Medicines”, the single ginseng soup is used to treat critical illnesses where the qi is deficient and the pulse is weak and dying. If other drugs are added with ginseng, it may have the disadvantage of adding to the problem, because the combined drugs may be evil or opposite as we know or don’t know, thus weakening the effect of ginseng in replenishing the qi and saving the off, and even producing toxic side effects. 2, hinder the doctor’s experience summary. There are many drugs in the formula, which is a big obstacle for doctors to summarize their experience in using medicine. Some doctors with insufficient clinical experience tend to seek comprehensive efficacy as soon as possible, the prescription is greedy for the whole. Such prescriptions are often disorganized, and even if they are fortunate enough to be effective, it is difficult for the doctor to understand the rationale for their effectiveness. For example, a patient who complains of headache, gastric distress, palpitations, painful urination, constipation and other symptoms is given a prescription for everything. What will the doctor conclude? Is the improvement in gastric distention only due to the effect of the medication for the stomach, or is it due to the medication for other symptoms? Why did the other symptoms not improve? Is it because the drugs for the other symptoms are ineffective, or is it due to the interplay between the drugs? It can be seen that the prescription is too large, which makes it very difficult for the doctor to evaluate the specific role of the drugs in the prescription. Another example of a simple case, such as the treatment of a dysentery patients, if the single use of drug A cure, we can clearly conclude that drug A has the effect of dysentery. But for the same patient, if the prescription for B medicine, C medicine cure, to determine their respective specific role is more difficult, may be B medicine has the effect of dysentery, and C medicine is not; may be C medicine has the effect of dysentery, and B medicine is not; may be B medicine and C medicine have the effect of dysentery. This is just a complex situation that occurs when two drugs are combined. When the doctor prescribes a dozen or even dozens of drugs, determine the effect of drugs will become very complex and difficult, which is very bad for doctors to sum up experience and improve the level of medication. 3. Increase the burden of patients. A large number of drugs in the prescription will bring extra burden to the patient in many aspects. First, it will increase the burden of the patient’s organism. In ancient times, Chinese medicine was called “poison” or “toxic medicine”, which means that compared with food, Chinese medicine has a greater bias and can have a more obvious effect on the human body. Therefore, food can be consumed daily, while herbal medicine should not be taken for a long time. In addition, after taking Chinese medicine orally, it must go through the process of absorption, distribution, metabolism and excretion. Excessive medication will increase the absorption burden of the gastrointestinal tract, stimulate the mucous membrane of the gastrointestinal tract, and easily cause symptoms of gastric discomfort; the metabolism and excretion of drugs mainly rely on the liver and kidneys, and excessive medication will also increase the burden of these two organs. Second, increase the economic burden of patients. China is still a developing country, and the income of a considerable part of the population is still very low, so the price of the whole prescription will be more expensive once there are more flavors of medicine, which will increase the economic pressure of patients. Large prescriptions make Chinese medicine lose its original advantage of being inexpensive and good quality. Third, it increases the burden of decoction for patients. After the doctor writes a large prescription, each post of medicine is so large that the patient needs a very large container to decoct it. Moreover, with more drugs and more liquid, the time for decoction will be extended accordingly. Thus, it can be seen that large prescriptions bring many burdens and inconveniences to patients. To sum up, clinicians must not simply think that prescribing more drugs is better than prescribing more drugs. If you want to become a good Chinese medicine doctor, you must study the herbs, familiar with the nature of the medicine, dialectical precision, grasp the main contradiction, and strive to achieve a concise prescription and effective macro is.