The severity of disulfiram-like reactions is directly proportional to the dose of applied drugs and the amount of alcohol consumed, and may be fatal, but not necessarily fatal, and there is a large individualized difference in how long it takes to kill. In milder cases, immediate cessation of alcohol consumption and emetic treatment, as well as drinking more water to promote excretion, usually lead to recovery on their own without special treatment. If patients have severe symptoms such as respiratory distress, anaphylaxis, drop in blood pressure and loss of consciousness, they must be sent to hospital immediately for infusion and given drugs such as epinephrine and dexamethasone, and most of them can be gradually relieved after treatment. Only individual patients with severe symptoms, complicated by multi-organ failure and airway obstruction, and did not seek medical attention in time, resulting in aggravation of the condition, and ultimately death due to ineffective resuscitation, but there is no exact clinical time on how long it takes to cause death. Disulfiram-like reactions are mostly due to alcohol consumption during the administration of cephalosporins and metronidazole, so alcohol must be strictly prohibited during the administration of such drugs. Disulfiram-like reactions may occur in people who take cephalosporin antibiotics within 5 days after drinking alcohol. It is recommended to drink alcohol for 6 days before taking the medication, which is usually safer.