Disulfiram-like reactions may occur when alcohol is consumed during the administration of cephalosporin, metronidazole, etc. The onset is usually rapid, occurring 15-30 minutes after drinking alcohol, and is generally safe if it takes more than 12 hours. When disulfiram-like reactions occur, patients may experience chest tightness, shortness of breath, blue lips, dyspnea, increased heart rate, decreased blood pressure, weakness of the limbs, facial flushing, excessive sweating, headache, nausea, vomiting, drowsiness, hallucinations, trance, etc. In severe cases, anaphylaxis may occur, with blood pressure dropping to 60-70/30-40 mmHg, accompanied by loss of consciousness, or even death. In addition, the severity of disulfiram-like reactions is directly proportional to the dose of applied drugs and the amount of alcohol consumed. In addition, drinking alcoholic beverages within 5 days before and after taking cephalosporins and other drugs may induce disulfiram-like reactions, so alcoholic beverages should be banned for as long as possible during and after the drug is stopped.