There is no clinical statement on which is better, Bifidobacterium triplex or quadruplex. Bifidobacterium triplex and quadruplex here mainly refer to Bifidobacterium triplex and Bifidobacterium quadruplex, which are two common microecological preparations that regulate the function of the gastrointestinal tract. The good or bad of these two drugs, Bifidobacterium triplex and quadruplex, should be judged according to the patient’s own constitution and condition. Both Bifidobacterium triplex and quadruplex have the function of regulating the dysbiosis in the gastrointestinal tract, improving the symptoms of abdominal pain, diarrhea, constipation and indigestion caused by the dysbiosis of the gastrointestinal tract, as well as maintaining the balance of the gastrointestinal tract flora, and the functions of the two drugs are basically the same as the main treatment of the disease. However, the types of live bacteria contained in the two drugs are different. In Bifidobacterium triplex preparation, it is mainly Bifidobacterium, Lactobacillus acidophilus and Enterococcus faecalis, while in Bifidobacterium quadruplex preparation, in addition to these three live bacteria, Bacillus cereus is also added. Generally, Bifidobacterium triad is preferred for treatment in clinical practice, and if the symptoms are not relieved after treatment, it can be replaced with Bifidobacterium quadruplex or other drugs for treatment under the advice of doctors. Therefore, when patients have symptoms such as diarrhea or indigestion caused by gastrointestinal flora imbalance, it is recommended to go to the hospital for relevant examination, so that the doctor can determine which drug is more suitable to use.