Case Share: 36-year-old Ms. Liang is a restaurant owner, usually business is very busy, but has been very concerned about maintenance, people to the middle age is still beautiful as a flower, the years have not left traces in her face; see Ms. Liang’s people say she looks only 30 years old. In recent times, the hotel’s business is very hot, but this time she was surprised to find that she had a bad change: the skin has grown a lot of spots, the body has gained weight, and this time to menstruation even menstrual cramps! Ms. Liang rushed to the hospital to do a checkup, after a detailed examination, Ms. Liang suffered from endocrine disorders; female endocrine disorders are not small, and are affecting the beauty and health, should receive treatment, endocrine regulation, early disorders of the endocrine into the right track. Want to understand the endocrine disorders, you must first know what is the gynecological endocrine system: The endocrine organs responsible for regulating the physiological functions of women are the hypothalamus, pituitary gland and ovaries. The hypothalamus is the leader, it secretes releasing hormones or inhibiting hormones to promote or prevent the secretion of pituitary hormones. The pituitary gland is in turn in charge of the ovaries. It secretes hormones: follicle stimulating hormone (FSH), luteinizing hormone (LH) and prolactin, the first two hormones known as gonadotropins, under their synergistic effect, the follicle in the ovary began to develop, mature, and secretion of estrogen; ovulation; ovulation and formation of corpus luteum and secretion of estrogen and progesterone. Estrogen has a wide range of physiological functions, mainly in the development of female reproductive organs, the formation and maintenance of female secondary sexual characteristics. In addition, it has the function of regulating the metabolism of each system of the whole body. Progesterone’s role is primarily limited to the uterus and is to prepare the endometrium to receive and nourish a fertilized egg. It also has a familiar and interesting role in raising the basal body temperature. It seems to be a hypothalamic-pituitary-ovarian cascade, but the estrogen and progesterone produced by the ovaries can, in turn, have a so-called “negative feedback” effect on the hypothalamus-pituitary, that is, when the concentration of ovarian hormones is elevated, the hypothalamus and the pituitary will be able to increase the basal body temperature. Concentration of ovarian hormone increases, the hypothalamus reduces the secretion of releasing hormone, the pituitary gland also reduces the secretion of gonadotropins, thus making the level of ovarian hormone also decreased; and the level of ovarian hormone is low, the hypothalamus and the pituitary gland and hasten to secrete the releasing hormone and gonadotropins, prompting the ovaries to produce a little more hormones. With this negative feedback, there are ups and downs of the menstrual cycle. The body’s natural hormones work together in harmony. So this is how the hormones work together for the body, so what are the negative consequences if this balance is broken? Broadly speaking, gynecological endocrine diseases cover a very wide range of diseases, which can be briefly divided into the following four major blocks: First, menstrual diseases, namely, menstrual disorders, amenorrhea, dysfunctional uterine bleeding, polycystic ovary syndrome, endometriosis, hyperprolactinemia and so on. The second block, infertility problems, any series of diseases that cannot accomplish normal reproductive functions are related to gynecological endocrinology. The third block, menopause-related diseases. Commonly known as menopause, most of the problems of female menopause are related to gynecological endocrinology, such as menopausal syndrome, tension incontinence, senile vaginitis, osteoporosis, knee dysfunction, lower limb muscular insufficiency and so on. The fourth block, some diseases related to sexual development. That is, abnormal sexual differentiation, breast dysplasia, precocious puberty, and delayed puberty. Tips: endocrine diseases can actually lead to infertility ah, want to have children of women can pay attention. If women have symptoms similar to those of Ms. Liang, they may want to go to the hospital for a checkup to rule out the cause of the disease or timely treatment to avoid delay!