Waking up with body aches and pains may be related to upper respiratory tract infections, over-exertion, or staying up late for a long time. 1. Upper respiratory tract infection: Failure to close the doors and windows in time while sleeping or having too thin a blanket may cause the body to get cold. Virus invasion of the body can lead to upper respiratory tract infection, inducing local inflammatory response, which may cause generalized soreness. 2. Overexertion: Doing a lot of exercise or overexertion before going to bed will produce a lot of lactic acid and metabolic waste. After waking up, the lactic acid cannot be discharged from the body or metabolized in time, which may also lead to waking up with generalized soreness. 3. Long time to stay up late: usually long time to stay up late, sleep time is too short, the body can not get enough rest, may also lead to wake up sore. Waking up with generalized pain may also be related to other reasons. It is recommended to go to the hospital as soon as possible, in order to clarify the cause of the disease, the cause of treatment.