Gluteus medius injury is one of the most common clinical lesions. Because the local symptoms of the lesion are often masked by the symptoms produced in its reflex zones, this condition can easily lead to underdiagnosis or misdiagnosis. Clinical pain and discomfort in the calf, foot, and ankle that are unexplained or poorly treated by conventional therapy are mostly related to injury to this muscle. The gluteus medius muscle is located on the deep side of the gluteus maximus, starting from the lateral iliac crest and ending at the greater trochanter of the femur. Its innervation originates from the superior gluteal nerve of L4 and 5S1. This muscle can abduct and internally rotate the thigh when contracted, and is one of the main abductor muscles of the hip. During unipedal stance, this muscle ensures the horizontal stability of the pelvis and is of great importance in maintaining normal standing and walking functions. Based on the position and function of the gluteus medius muscle, people are prone to injury of this muscle in daily life, sports and labor. In particular, lateral swing of the trunk with the hip as the apex (e.g., when foot pronation is sprained, the ipsilateral hip twists to the side due to the effect of gravity and inertia) and twisting of the waist and hip with the hip as the axis (e.g., throwing action) often lead to strain injury of this muscle. Damage to the gluteus medius muscle caused by drugs and mechanical stimulation during hip muscle injection should not be overlooked either. Due to the strong compensatory role of the gluteus maximus and vastus lateralis, some of the dysfunction caused by gluteus medius injury may not produce significant local symptoms and is therefore easily overlooked. However, the injury is objective. The pathological impulses generated by the gluteus medius injury, via the L4 and 5S1 spinal nerve segments, reflexly cause pain or numbness or swelling in the distal end of the ipsilateral knee. Patients show discomfort in the affected calf, swelling, and need pounding or massage to relieve. Intermittent limp symptoms appear when walking longer distances. In severe cases, the calf is painful to the touch, but the patient feels comfortable for a short time instead of pressing hard, which affects walking and sleeping. When the knee joint is straightened, the calf sometimes has “cramping” symptoms. It is usually diagnosed as “calf restlessness syndrome” or “spinal stenosis” or “traumatic arthritis”. In some cases, the symptoms are only pain and discomfort in the foot and ankle, plantar numbness and swelling, and pain in the heel, metatarsal bunion and metatarsal phalangeal joint. All of the above symptoms are more dramatic at the beginning of the activity, and after the activity is unfolded, the symptoms are slightly relieved, and then aggravated after exertion. Therefore, the diagnosis of “gluteus medius injury syndrome” should be considered for some unexplained or foot and ankle injuries (e.g. inversion sprain, ankle fracture) that still leave pain and discomfort in the lower leg, ankle and metatarsophalangeal joint for a long period of time after the affected limb is cured, and the conventional treatment has little effect. Physical examination: painful striations can be palpated on the anterolateral and posterior sides of the gluteus medius muscle. There may be ipsilateral hip and sacral distension and unbearable numbness and swelling of the knee joint at the distal end when pressure is applied.