Stool with mucus and a small amount of blood may be ulcerative colitis, bacillary dysentery, colorectal cancer and other disease factors caused by the need for targeted treatment under the guidance of a doctor, such as drug therapy, surgical treatment. 1. Ulcerative colitis: Sulphasalazine is suitable for the treatment of mild to moderate active ulcerative colitis, glucocorticosteroids, such as prednisone, etc. can control the activity of the disease, accompanied by intestinal perforation can be surgical treatment. 2. Bacterial dysentery: it can be treated with antibacterial drugs, such as ceftriaxone, ciprofloxacin, etc. When accompanied with dehydration, it can be treated with rehydration, and when accompanied with severe diarrhea, it can be treated with loperamide to stop diarrhea. 3. Colorectal cancer: Early colorectal cancer can be treated by endoscopic treatment, such as endoscopic mucosal resection, endoscopic submucosal dissection, etc. Surgical treatment mainly involves radical surgical resection, and can be combined with chemotherapy and radiotherapy. It is recommended to go to the hospital when the symptoms of mucus with a small amount of blood in the stool occur, and ask the doctor to make a judgment and formulate a treatment plan.