CIN refers to cervical intraepithelial neoplasia. Cervical CIN Grade II involving glands is Grade II cervical intraepithelial neoplasia. The severity of its condition is related to whether the treatment is timely or not, and the patient’s health condition. Generally speaking, the progression of the lesion can be effectively prevented by early detection and timely treatment, but it can be life-threatening if not treated in time. Cervical intraepithelial neoplasia is generally associated with human papillomavirus infection. Grade II cervical CIN is equivalent to precancerous lesions. Patients may experience symptoms such as increased vaginal discharge and abnormal vaginal bleeding, which require early treatment. For cervical CIN grade 2, doctors usually recommend surgical treatment, and the specific surgical methods include cervical cerclage, cold knife conization of the cervix, and so on. In addition, total hysterectomy can be considered if the pathology after conization confirms the diagnosis of high-grade cervical intraepithelial neoplasia or residual lesions at the margins, and the patient does not have fertility requirements. With early detection and timely surgical resection, the prognosis of grade II cervical CIN is generally good, and further development of the lesion can be prevented. However, if not treated in time, it can further develop into cervical cancer, which seriously affects the quality of life and survival time of patients. Patients with CIN grade II involving the gland should seek timely medical attention and actively cooperate with their doctors.