Recurrent fever can occur with viral infections, and it is of utmost importance that the appropriate virus should be identified for cause-specific treatment. In case of varicella-zoster virus infection, which can show obvious symptoms and is easier to diagnose clinically, antiviral treatment such as acyclovir can be applied. In the case of cytomegalovirus infection, antiviral drugs such as ganciclovir or sodium fosfomate can be applied. And influenza virus infection can be applied with antiviral drugs such as oseltamivir, or paramivir. Once the corresponding pathogen is identified, antiviral drugs can be targeted for treatment and the corresponding fever symptoms can usually be improved. In some viral infections, there are no targeted antiviral drugs, but most of them are self-limiting, and fever recurrence occurs, probably because the viral infection is long-term and chronic, but there are no well-targeted antiviral drugs. In addition, factors other than viral infection should be considered, such as autoimmune diseases or other factors other than infection that cause fever, which may recur despite the application of more targeted antiviral drugs, so it is important to find the cause.