A two-positive, one-negative postoperative breast cancer pathology report is one that has a better prognosis than other molecular types (e.g., triple-negative, HER2-positive). The so-called “two-positive, one-negative” refers to the molecular typing of breast cancer as hormone receptor-positive (including estrogen receptor and progesterone receptor) and HER2-negative, which accounts for 60% of all molecular typing, and is the most common type of breast cancer, with a significantly higher 5-year survival rate than that of triple-negative and HER2-positive breast cancers. . In clinical practice, molecular typing alone is not sufficient to evaluate the severity of the disease (i.e., the risk of recurrence and metastasis). Doctors also need to know the risk factors such as lymph node metastasis, size of the mass, age, menstrual status, family history and other factors to make a comprehensive consideration, so it can only be said that “two positives and one negative” is a relatively less severe type of breast cancer. It is recommended to follow the doctor’s advice and actively cooperate with the treatment to improve the prognosis, do not be negligent, so as to avoid delaying the condition and affecting the therapeutic effect.