Treatment for male breast enlargement can be handled through observation, oral medication as prescribed by the doctor, and surgery, depending on the cause of the breast enlargement and the extent of the condition. Adolescent males may also experience breast enlargement, resulting in slightly enlarged breasts and small hard nodules under the nipple. Generally, no special treatment is needed, but changes in breast size and the size of the lumps should be observed regularly. It can be treated with oral anti-estrogen drugs clomiphene and tamoxifen. If the drug treatment is ineffective, surgical treatment is considered, and simple mastectomy is feasible; for hyperplasia of both breast tissue and subcutaneous fat, it is treated by liposuction and mastectomy. In addition, some male breast enlargement is caused by the application of drugs or systemic diseases, need to stop using the relevant drugs or treat the relevant diseases. If a man is diagnosed with breast enlargement, he should go to the hospital in time and under the guidance of the doctor to identify the cause of the disease and carry out targeted treatment, so as to avoid delaying the disease and causing adverse consequences.