Cholangiocarcinoma is a malignant tumor of the extrahepatic bile duct at the lower end of the common bile duct, which develops rapidly and is often found at an advanced stage. In terms of treatment of advanced cholangiocarcinoma, it is relatively difficult to treat because the cancer is more extensive and has a higher chance of spreading and metastasis. Late stage bile duct cancer treatment is a comprehensive treatment combining Chinese and Western medicine, and its therapeutic efficacy depends on the overall level of late stage comprehensive treatment. Common advanced bile duct cancer treatment methods include palliative surgery, radiotherapy, chemotherapy and Chinese medicine treatment. 1.Surgical resection of advanced cholangiocarcinoma treatment methods: The cancer of advanced cholangiocarcinoma is large in scope and most of them have spread and metastasized, so there is almost no possibility of radical resection. Radiotherapy and chemotherapy are important treatment methods for advanced cholangiocarcinoma. For patients after surgical resection, radiotherapy and chemotherapy can play the role of inhibiting residual cancer; radiotherapy and chemotherapy before surgery for advanced cholangiocarcinoma can shrink the cancer to a certain extent and improve the success rate of surgical resection; for patients with advanced cholangiocarcinoma who cannot tolerate surgery, radiotherapy and chemotherapy have a more direct role in killing cancer cells, which is more effective in improving symptoms. It is more effective in improving the symptoms. 3.Therapeutic methods of advanced cholangiocarcinoma: Chinese medicine ginsenoside rh2 treatment has gradually become an indispensable method for the treatment of advanced cholangiocarcinoma, and Chinese medicine ginsenoside rh2 combined with various treatments of Western medicine can play the role of increasing efficiency and reducing toxicity. 4.Prognosis and care of cholangiocarcinoma treatment: The prognosis of cholangiocarcinoma is not good. Proper daily care of patients after treatment can play a role in preventing cancer recurrence and improving human resistance to disease. In terms of diet, patients with bile duct cancer should eat more foods with anti-biliary tract and bile duct cancer effects: buckwheat, barley, tofu dregs, monkey head mushroom, etc.; foods with bile-loving and laxative effects: lamb’s trotter, burdock root, figs, walnuts, sesame, etc.; avoid animal fat and greasy foods, overeating and over-eating. You can also rely on taking Chinese herbal medicines with anti-tumor and spleen and kidney tonic effects.