Acne can be caused by diseases such as acne, folliculitis, and facial disseminated milia lupus, etc. Since each disease has a different etiology, the causes of recurring acne are also different. 1. Acne: Acne is mainly related to high androgen levels, abnormal secretion of sebaceous glands, abnormal keratinization of cells around hair follicles, and skin infections with Propionibacterium acnes, and often manifests itself in the form of pimples, papules, pustules, and nodules. If patients have bad habits, such as staying up late, smoking and drinking, eating oily and spicy food, not paying attention to skin cleansing, etc., the phenomenon of repeated acne may occur. 2. Folliculitis: daily inattention to local skin cleaning, resulting in hair follicle blockage and bacterial infection can induce folliculitis, often manifested as redness, swelling and pain in the tissues around the hair follicle. If the patient has certain underlying diseases, such as diabetes, AIDS, etc., the body’s immunity is lowered, and the phenomenon of repeated growth of acne may occur, and in severe cases, boils and cellulitis may also occur. 3. Facial disseminated milia lupus: the cause of this disease is not yet clear, often manifested in the face as several isolated light red papules, on which there may be small pustules, without conscious symptoms, usually through typical skin lesions and routine pathological examination for diagnosis. Because the cause of the disease is not known, so there is no specific drug treatment, only symptomatic treatment, so the condition is easy to repeat, can be manifested as the phenomenon of repeated growth of acne. There are many reasons that lead to repeated growth of acne, it is recommended that patients go to the hospital in a timely manner for a clear diagnosis, under the guidance of the doctor to choose a standardized, targeted treatment, so as to solve the problem of acne.