There is no documented evidence that the use of Zhi Bai Di Huang Wan can worsen precocious puberty in girls. Girls with precocious puberty need to seek medical advice from regular hospitals in order to avoid delaying their condition. Zhi Bai Di Huang Wan is composed of Zhi Mu, Shu Di Huang, Mudan Pi, Ze Xie Di and other traditional Chinese medicines, which can nourish the kidney yin and lower the fire, and can be used clinically to treat hot flashes (a burst of fever), sore throat, night sweating (abnormal sweating after going to sleep, but sweating stops after waking up) caused by yin deficiency and fire exuberance (Yin essence deficiency and hyperactivity of deficiency fire in the body), self-consciousness of a dry mouth, ringing in the ears, spermatorrhea in males, and low volume of urination, increased frequency of urination and other conditions. Diseases. Contraindicated if allergic to Zhi Bai Di Huang Wan. Allergic persons should be cautious. There have been no known adverse drug reactions after taking Zhi Bai Di Huang Wan. Pregnant women should take with caution. Not suitable for patients with deficiency cold syndrome, which is characterized by fear of cold, cold hands and feet, and preference for hot drinks. It should not be taken at the same time with cold and flu medicines. Clinical identification of precocious puberty in girls belongs to the Yin deficiency and fire can be taken under the guidance of a professional Chinese medicine practitioner, the specific use of drugs need to strictly comply with the doctor’s instructions.