Watery eyes from wiping the nose can be caused by nasal secretions and fluid from the nasolacrimal duct backing up at the eyes. In normal humans, there is a physiologic passage between the eye and the nasal cavity called the nasolacrimal duct. The opening and lower end of the nasolacrimal duct are anatomically narrow segments that are susceptible to obstruction by nasal pathology. There is a small amount of fluid in the nasolacrimal duct, and when a person suffers from cold and flu, allergic rhinitis and other causes of nasal secretions increase, it is easy to cause the lower opening of the nasolacrimal duct to be occluded, resulting in poor drainage of tears to the nasal cavity. In addition, wiping the nose can cause nasal pressure is too high, easy to lead to nasal secretions and nasolacrimal duct in the liquid reflux into the eyes. As a result, watery eyes can be seen when wiping the nose. If you have watery eyes after wiping your nose, you should go to the hospital for timely treatment to avoid further development of your condition.