First generation IVF and second generation IVF refer to IVF techniques, and there is no such thing as better quality, just different fertilization methods and different target groups. The first generation of IVF is to let sperm and egg fertilize naturally outside the body, and then implant the embryo into the woman’s uterus, which is closer to the natural mode of conception, and is suitable for women with endometriosis, tubal blockage and other diseases, while the sperm of men is in good condition. The second generation of IVF is used for people whose male sperms are in poorer condition or those who have failed in the first generation of IVF. High quality sperms need to be injected into the eggs with a puncture needle under a microscope to fertilize the eggs, and this operation may be traumatic to the eggs, so the success rate of the second generation of IVF is lower than that of the first generation of IVF. It is recommended that when doing IVF, you should follow the guidance of professional doctors, choose a suitable program for yourself according to your own situation, and maintain a good mindset and lifestyle can improve the success rate of IVF.