The duration of gastric cramps is correlated with the primary disease and there are individual differences, ranging from a few minutes to ten minutes or several hours. Gastric spasm episodes are often triggered by poor diet, drug stimulation, and other triggers on top of an underlying gastric disease. Common underlying gastric diseases include peptic ulcer, chronic gastritis, tumor, pyloric obstruction, food poisoning, etc. They manifest as severe contractions of the stomach muscles, resulting in pain. Spasms caused by inflammation or drug stimulation are usually short-lived, usually relieving themselves in a few minutes or less, but can recur, but the patient’s pain is naturally relieved after the inflammation is controlled. Spasmodic pain induced by stomach tumors and peptic ulcers lasts longer because the trigger cannot be removed in a short time, and the pain can last for tens of minutes to hours and can recur under certain triggers. Treatment of gastric cramps should be directed at the etiology and symptomatic treatment, such as anti-inflammatory drugs if it is caused by inflammation; peptic ulcer requires the application of PPI-type drugs and eradication of H. pylori. Symptomatic treatment can be applied to antispasmodic drugs, such as scopolamine or atropine can play a role in relieving gastrointestinal spasm.