The presence of lumbosacral pain may be caused by pelvic inflammatory disease. Women with pelvic inflammatory disease may experience pain in the lower abdomen, which is usually persistent, and the inflammation may stimulate the nerves in the lumbar region, resulting in lumbosacral pain. It may also be caused by uterine fibroids, which are large in size and cause the entire uterus to increase in size, compressing the nerves in the lumbar region and causing pain in the lumbosacral region. If the pain is caused by pelvic inflammatory disease, you need to actively apply anti-inflammatory drugs for anti-inflammatory treatment, and often choose broad-spectrum antibiotics, such as cephalosporin and tinidazole, or etimesine sulfate, for about ten days. If it is caused by uterine fibroids, surgery is needed to remove the fibroids to cure it.