The main chemotherapy drugs for colon cancer are 5-fluorouracil, calcium folinic acid, oxaliplatin, tegeo, capecitabine, etc. These drugs are mainly composed of 5-fluorouracil and oxaliplatin, or 5-fluorouracil and irinotecan resulting in FOLFOX regimen or FOLFIRI regimen. FOLFOX is mainly used for adjuvant chemotherapy after colon cancer surgery, while FOLFIRI regimen is mainly used for metastatic colon cancer. FOLFOX is mainly used for postoperative adjuvant chemotherapy of colon cancer, while FOLFIRI is mainly used for metastatic colon cancer, and other adjuvant chemotherapy including oral capecitabine and tegretolimus can be applied to colon cancer alone.