The causes of low ratio of large platelets include physiological and pathological causes (such as primary thrombocythemia).
1. Physiological reasons: in case of bleeding such as surgery, trauma, etc., the coagulation function of the human body will be activated, and a large number of large platelets will be converted into small platelets to coagulate and stop bleeding, which will lead to a decrease in the proportion of large platelets in the blood.
2. Pathological reasons: mainly due to the bone marrow hematopoietic function abnormalities caused by large platelet ratio decreased, small platelet ratio increased, such as aplastic anemia and so on.
In addition to the above reasons, leukemia and other diseases may also cause low ratio of large platelets. It is recommended to go to the hospital to check the cause of the disease and give targeted treatment under the guidance of the doctor.