Betalucil is generically known as metoprolol tartrate and Shubisan is generically known as indapamide tablets, both of which are able to be taken together with valsartan. Clinically, metoprolol tartrate belongs to the beta receptor antagonist, after taking it can inhibit myocardial contractility and slow down the heart rate, mainly used for hypertension, angina pectoris and other diseases treatment. The drug may cause dizziness, headache and other discomforts after taking it. It is contraindicated for people with cardiogenic shock. It needs to be used with caution when used in combination with other antihypertensive drugs to avoid hypotension caused by drug overdose. Pregnant and lactating women need to use the drug under medical supervision. Indapamide tablets belong to the sulfonamide derivative of the indole ring, also belongs to the diuretic, after taking it can inhibit the role of sodium reabsorption, increase the excretion of substances in the urine. It is mainly used in the treatment of essential hypertension. The drug may cause discomfort such as dry mouth and dizziness after taking it. It is contraindicated in severe hepatic and renal insufficiency. When taking the drug, it is necessary to pay attention to changes in blood pressure and blood calcium. Pregnant and lactating women need to use the drug under doctor’s supervision. Valsartan belongs to the angiotensin II receptor antagonist, after taking it can inhibit vasoconstriction and aldosterone release, mainly used for the treatment of mild and moderate essential hypertension. Usually after taking it, you may experience discomfort such as elevated serum potassium, dizziness and cough. Allergic to the components of the drug is prohibited, liver and kidney function and blood pressure need to be monitored in the process of taking the drug, pregnant and lactating women need to use the drug under the guidance of a doctor. To summarize, the above three drugs are all antihypertensive drugs. If a combination of drugs is needed due to the condition of the patient, it is recommended to consult the cardiovascular department in time, and the doctor will decide on the combination of drugs after a comprehensive assessment of the condition of the patient.