The possible causes of lumbar vertebrae pain by pressure include lumbar muscle strain, lumbar disc herniation, lumbar spine slip, lumbar isthmus fracture, tuberculosis or tumor of lumbar vertebrae, and so on. 1. Lumbar muscle strain: the lumbar muscle, due to uneven stress, inflammation, lumbar intervertebral disc herniation and other factors, may induce spasm of the muscle tissue around the lumbar vertebrae, which leads to the whole lumbar muscle being in a tense and hardened state, and at the same time, there is pain when pressing. 2. Herniated lumbar intervertebral disc: it may be due to the rupture of the annulus fibrosus of the lumbar intervertebral disc, the nucleus pulposus protrudes and squeezes the nerve root, which causes lumbar vertebrae to be painful to press. 3. Lumbar spondylolisthesis: it may be caused by degeneration, trauma and other factors, resulting in vertebral body misalignment, leading to lumbar spondylolisthesis, which compresses the lumbar spinal nerves, thus generating lumbar vertebrae pressing pain phenomenon. 4. Lumbar isthmus fracture: it may be caused by congenital dysplasia or isthmus stress fracture, and the main symptom is lower back pain, which may also cause lumbar vertebrae pressing pain. 5. Tuberculosis or tumor of lumbar vertebrae: Tuberculosis or tumor of lumbar vertebrae may destroy the bone quality of lumbar vertebrae and invade lumbar vertebrae nerves, which may cause lumbar vertebrae pressing pain. Lumbar vertebrae pressure pain may also have other reasons, it is recommended to go to the regular hospital in a timely manner to improve the relevant examination, clear the cause of the disease, under the guidance of the doctor to carry out targeted treatment or treatment.