Itchy nipples can squeeze out water may be eczema, nipple inflammation, breast cancer and other causes, patients should consult a doctor in a timely manner to clarify the cause of the corresponding treatment. 1. Eczema: itchy nipples can squeeze out water may be caused by eczema, mostly in lactating women, patients will have local redness, swelling, skin lesions, can use tacrolimus, loratadine and other drugs for treatment. 2. Nipple inflammation: most common in primigravida, may be the nipple skin breakage secondary infection, the patient will have nipple itching, can be squeezed out of the water, fever and other symptoms, can use penicillin, metronidazole and other drugs for treatment. 3. Breast cancer: nipple can be squeezed out of the water, itching may also be caused by breast cancer, such patients will also have areola abnormality, breast lumps, axillary lymph node enlargement and other symptoms, it should be timely surgery, radiotherapy, chemotherapy and other comprehensive treatment. In addition, breast hyperplasia, breast cysts, breast trauma may also appear similar clinical manifestations, once the nipple itching can squeeze out water, we should consult a doctor in a timely manner, to clarify the cause of the disease, under the guidance of the doctor for treatment.