Hairy gallbladder is considered a finding of gallbladder ultrasound. Healthy people do not need medication; if there is cholecystitis, generally take cholecystectomy, those who can not tolerate surgery can take non-surgical treatment, you can take antibiotic drugs, such as cephalosporins (cefadroxil tablets, cefuroxime tablets), quinolones (norfloxacin capsules, ofloxacin tablets) and so on. 1. No need for medication: gallbladder roughness, is a result of ultrasound, can also be seen in normal people, if the body does not have any symptoms generally do not need to use drugs. 2. Cholecystitis: for example, obstruction of the biliary tract, bacterial infection, or stones in the biliary tract may cause cholecystitis, which may also be manifested in the results of ultrasound examination of the gallbladder roughness, and at the same time, the blood routine will find that the total number of leukocytes and neutrophil counts are elevated. Generally, cholecystectomy is taken, and those who cannot tolerate surgery can take non-surgical treatment. (1) Cephalosporins: commonly used drugs include cefadroxil tablets, cefuroxime tablets, cefoxitin capsules and so on. Common adverse reaction is allergic reaction, then skin rash, itching, etc., allergic to the drug is prohibited. (2) Quinolones: commonly used drugs are norfloxacin capsules, ofloxacin tablets, ciprofloxacin tablets and so on. Common adverse reactions include nausea, vomiting, abdominal pain, diarrhea, etc. Occasionally, rash, itching and other allergic phenomena. People who are allergic to the drug are forbidden to use it. If there is any disease in the body, you should go to the hospital for examination in time, and all medicines should be used under the guidance of professional doctors.