Infection after amputation should first go to the hospital to clean the wound and change the dressing, and follow the doctor’s instructions to take antibiotics. Pay attention to daily diet and local hygiene. After amputation, if the wound is not properly cared for and prone to infection, you need to go to the hospital to use iodine povidone to clean the wound, and change the dressing in time. If the deep wound infection is caused by peripheral vascular lesions, it is usually necessary to clean and irrigate the wound in the operating room and open the wound. At the same time, according to the results of bacterial culture, should also be given the appropriate antibiotic treatment, commonly used drugs are amoxicillin, cefradine, gentamicin and so on. In order to prevent infection after amputation, it is important to do a good job of local cleaning and avoid strenuous exercise. Diet should avoid spicy stimulation, should not smoke and drink alcohol. Try to choose protein, milk, soy milk and other foods to supplement nutrition. The use of drugs need to follow the doctor’s instructions.