Should we test the fragmentation rate of sperm or not? I think it is very important in the clinical testing function. He is closely related to the outcome of pregnancy. We all know that the number and viability of sperm determines the ability to conceive, but after pregnancy, will the embryo survive successfully or not? Early miscarriage or biochemical abortion are closely related to the fragmentation rate. My personal recommendation. Men routinely have their sperm fragmentation rate tested during fertility testing. Of course these tests are not available in many hospitals and not all hospitals carry them out. Sperm DFI is associated with male infertility and early recurrent miscarriage in their partners, but there are various reasons for increased sperm DFI. Increased sperm DFI is detrimental to normal fertilization and embryonic development. Increased sperm DFI can be caused by maturation defects and apoptosis occurring in the testis, or by peroxidation (ROS) in the male reproductive tract. It can also be caused by external factors including clinical disease states (varicocele, cancer, diabetes), inflammatory conditions of the reproductive system (male urinary tract infections, mycoplasma chlamydia infections, epididymitis, orchitis, prostatitis, seminal vesicles), lifestyle risk factors (smoking, alcohol abuse, obesity, poor lifestyle) and environmental exposures (air pollution, pesticides, industrial chemicals, formaldehyde, gasoline We hope that eugenic men will routinely undergo this sperm test.