1.Surgical treatment Surgical resection is still the first choice to cure early gastric cancer. For early gastric body and sinus cancer, distal radical subtotal gastric resection is performed, while proximal subtotal gastric resection or total gastric resection is performed for gastric base cancer. (1) For stage I and II gastric cancer, radical surgery should be the main treatment. After surgery, stage II gastric cancer should be treated with necessary chemotherapy plus traditional Chinese medicine anti-cancer treatment. (2) Stage III gastric cancer, radical surgery for gastric cancer should be adopted as far as possible, and palliative resection can be adopted when radical surgery is not possible; preoperative chemotherapy should be done first, which is helpful to destroy cancerous tissues, shrink the tumor, promote peri-cancerous fibrosis, eliminate peri-cancerous and inflammatory adhesions, and improve surgical resection rate, and postoperative anti-cancer supplemented with chemotherapy plus immunotherapy to reduce postoperative recurrence and metastasis. (3) For stage IV gastric cancer, if the patient’s general condition is good and there is no extensive metastasis, palliative resection or short-circuit surgery is adopted as far as possible, and postoperative chemotherapy is combined with anti-cancer supportive therapy; if the patient’s general condition is poor, immunotherapy alone can be used. (4) Patients with advanced gastric cancer have undergone surgery, and although the cancer has been removed, the cancer foci still exist. If there are cancer stray cells in blood vessels or recurrent metastasis after surgery, supportive therapy and combined with radiotherapy and chemotherapy can be used for comprehensive treatment. 2.Chemotherapy: Gastric cancer is mostly adenocarcinoma, and often 5-fluorouracil (5-Fu), mitomycin (MMC), adriamycin (ADM) and methylcyclic nitrosourea (Me-CCNU) are used. (1) FAM regimen: ①5-Fu 500mg on day 1, then once a week; or 5-Fu 500mg daily for 5 days, then repeat every 3 weeks for 5 days. ②ADM 30-50mg on day 1, then repeat every 3 weeks. (3) MMC: 4~10mg on day 1 and repeat every 3 weeks. (2) EAP regimen: ①ADM 20mg/m2, iv, d1-7; ②DDP 40mg/m2, iv, d2-8; ③VP-16 100mg/m2, iv, d4, 5, 6; 3~4 weeks as a course of treatment. (3) MFV regimen: ①MMC 6mg/m2, iv, 1/3W; ②5-FU 400mg/mg2, iv, 1/day x 4/3W; ③VCR 1.4mg/m2, iv, 1/W x 2; 3 weeks as a cycle, three cycles as a course. (4) Furanyl fluorouracil (FT-207) 200mg per dose, 1 day 3 to 4 times orally. FT-207 is a derivative of 5-Fu, which can replace fluorouracil. 3.Chinese medicine treatment: Chinese medicine treatment for gastric cancer has good effects on improving symptoms, enhancing immune function, stabilizing the balance of internal environment, protecting normal functions of organs, prolonging survival and promoting recovery, which are difficult to be replaced by any kind of western medicine. The principle of Chinese medicine treatment for gastric cancer is to support the positive and dispel the evil. “Support the positive” means to regulate the balance and stability of human body functions and enhance its own anti-cancer ability, while dispel the evil means to eliminate cancer foci, kill cancer cells and control their proliferation. 4.Immunotherapy It is inappropriate to use immunotherapy alone for gastric cancer patients. Immunotherapy, complemented with chemotherapy, can improve patients’ ability to resist cancer, reduce metastasis and recurrence, improve survival rate and prolong life. BCG (BCG vaccine) is most commonly used, usually 5mg of BCG (the number of raw bacteria is about 2-4×108) is applied on the skin of wrist, and then a needle tip is used as a bet. BCG can enhance non-specific immune response, and OK-32 has the same effect. 5.Intraoperative radiation therapy Patients with pathologically confirmed stage II or III gastric cancer and basically normal cardiopulmonary function can be supplemented with intraoperative irradiation therapy with a one-time irradiation of 20-30 Gy. Although the addition of intraoperative radiation therapy for gastric cancer can improve the survival rate of patients, the general trend is difficult to promote. 6.Gastric cancer monoclonal antibody only binds to gastric cancer cells, but does not react with normal tissues or other tumor cells. If combined with anti-cancer drugs and some cytotoxic, monoclonal antibodies can play a “biological missile” effect, its role in killing local cancer cells can be enhanced dozens of times to hundreds of times, especially the post-operative spread of cancer cells kill more, so you can reduce the amount of anti-cancer drugs, reduce the side effects of drugs, thereby improving the therapeutic effect.