Gastric cancer is one of the most common gastrointestinal malignancies, and its mortality rate is second only to lung cancer. So far, comprehensive treatment is still the most effective measure to treat gastric cancer, i.e. surgery is the main treatment as far as conditions permit, supplemented by multidisciplinary treatment such as radiotherapy, chemotherapy, Chinese medicine and cellular immunotherapy to improve patients’ symptoms, improve life quality and prolong survival. Surgery: Surgery is one of the main and preferred means of gastric cancer treatment. If the patient’s physical condition allows and there is no distant metastasis, radical surgery can remove the tumor and regional metastases, while palliative surgery can not only relieve the clinical symptoms and improve the quality of life, but also create favorable conditions for radiotherapy, chemotherapy and traditional Chinese medicine treatment. Radiotherapy and chemotherapy: radiotherapy and chemotherapy combined with surgery can improve the efficacy of comprehensive treatment of gastric cancer. Preoperative radiotherapy and chemotherapy can control or shrink lesions, so that some patients with unresectable and locally infiltrated gastric cancer can receive surgery; intraoperative radiotherapy and chemotherapy can reduce potential lymphatic and hematological metastasis caused by surgical operation; postoperative radiotherapy and chemotherapy can effectively prevent recurrence and metastasis. However, radiotherapy and chemotherapy have certain toxic side effects. Chinese medicine treatment: Chinese medicine has the function of supporting the righteousness, regulating the immune function and strengthening the body. On the one hand, Chinese medicine can reduce the damage of radiotherapy and chemotherapy and speed up the recovery of patients’ body functions, on the other hand, Chinese medicine also has anti-tumor effect, which can prolong the survival period and improve the quality of survival to a certain extent. Cellular immunotherapy: Cellular immunotherapy is an emerging tumor treatment technology, which means that autologous immune cells that can kill tumor are cultured in vitro and then infused back into the body to kill tumor cells to improve the therapeutic effect of gastric cancer treatment.