Children sleeping suddenly waking up in the middle of the night and talking to themselves are mostly seen in sleep environment factors, stimulation during the day, over-excitement before going to bed, parasitic infections, sleepwalking and so on. 1. Sleep environment factors: If the environment in which the child sleeps is too noisy, and the child is woken up during sleep, this phenomenon may occur. 2. Stimulation during the daytime: it may be that the child has watched a more intense scene during the daytime or has been scolded by his parents, which may easily lead to disturbed sleep and babbling at night due to certain mental stimulation. 3. Over-excitement before bedtime: if children play too much before bedtime, it will lead to high excitability of the cerebral cortex, restless sleep, and easy to wake up in the middle of the night, talking to themselves. 4. Parasitic infections: Parasitic infections in the intestines or bile ducts may easily affect sleep and lead to waking up in the middle of the night. 5. Sleepwalking: It may be caused by sleep deprivation or sleep disorders, and may wake up in the middle of the night and talk to themselves. Children suddenly wake up in the middle of the night, talking to themselves, there may be other reasons, it is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.