Creatine kinase is most abundant in skeletal muscle, cardiac muscle, and smooth muscle. The normal value is 18-198 U/L, which is a diagnostic item for cardiomyopathy. Creatine kinase 200U/L is mostly slightly high and may be physiologically elevated. The following reasons are common: First, high creatine kinase after strenuous exercise, which can be ruled out as long as the review is done in a quiet state. Second, the installation of pacemakers, radiofrequency ablation surgery, can also lead to elevated creatine kinase. Third, drugs can also lead to elevated creatine kinase, such as lipid-lowering statins, which can be identified by reexamination after a week of discontinuation. Pathological elevation is myocardial infarction, viral myocarditis or heart failure, are accompanied by symptoms, not just abnormal laboratory results, such as heart attack will have severe chest pain, and the dynamic evolution of the electrocardiogram, myocarditis before the onset of viral infection period, clinical manifestations can have fever, panic, chest tightness, weakness and so on.