The leg swelling of cerebral infarction patients may be caused by deep vein thrombosis of the lower limbs, and the venous ultrasound of the lower limbs should be checked. If there is thrombosis, anticoagulation therapy should be given in time, commonly used drugs include low molecular heparin and warfarin, and if necessary, interventional embolization therapy is also available. Patients with cerebral infarction who have lower extremity deep vein thrombosis are usually seen in large hemispheric infarction and brainstem infarction, and the clinical symptoms and signs of these patients are usually heavy, and most of them may have hemiparesis, hemianesthesia and hemianopsia. Patients with brainstem infarction may also present with quadriplegia and bulbar palsy, and in severe cases may present with impaired consciousness, including lethargy, somnolence, and coma, as well as cerebral edema and increased intracranial pressure. Patients in this category are usually in the recumbent position, and prolonged bed rest can easily cause deep vein thrombosis of the lower extremities. Therefore, for patients with large cerebral infarction who are bedridden for a long time, rehabilitation treatment should be given as early as possible, mainly limb rehabilitation exercises, and pneumatic therapy can be given if necessary to prevent deep vein thrombosis.