Puncture is suitable for patients with pleural effusion or large amounts of fluid in the abdominal cavity. The purpose of puncture is to clarify the nature of the effusion as well as to further eliminate the fluid, which can relieve the symptoms. The purpose of the puncture should be explained in detail to the patient before the puncture, to eliminate nervousness, and preferably to localize the patient. For patients with encapsulated effusion, preoperative localization by ultrasound or CT guidance can be chosen, and puncture by guidance can also be performed if necessary. For failing patients, the option of positioning at the bedside for puncture or tube placement. In the operation process, it should be careful to avoid the site of obvious soft tissue infection, as well as the site of localized fracture after trauma, because the puncture will lead to the appearance of collateral damage, and even induce the worsening of the patient’s pain symptoms.