Enteritis retroperitoneal multiple small lymph nodes are usually enlarged lymph nodes caused by infection, and the infectious agent of enteritis enters the local lymph nodes through blood circulation, resulting in mesenteric or retroperitoneal lymphadenitis. It usually manifests with symptoms such as fever, abdominal pain and bloating. Enteritis retroperitoneal multiple small lymph nodes can be treated by anti-infective drugs, such as levofloxacin and ceftazidime. Levofloxacin is used to treat infectious enteritis and so on, and should not be used by patients who are allergic to quinolones. It is recommended that patients should pay attention to the dietary rules and hygiene in daily life, avoid overeating, eating spicy, greasy, cold and other stimulating foods. Patients should use medication reasonably under the guidance of the doctor, do not use medication privately, so as not to cause danger.