Autoimmune liver disease treatment time can not be generalized, because each patient’s condition is different, the use of the treatment program will be different, the treatment cycle will naturally be different, and part of the patient’s condition may be recurrent, then the treatment time will be longer, the more serious the condition of the patient required treatment cycle is generally relatively longer. Autoimmune liver disease is a type of liver disease, which is caused by abnormalities in the autoimmune system leading to damage to the health of the liver function, and can be divided into five different types: autoimmune hepatitis, primary biliary cirrhosis, primary sclerosing cholangitis, overlap syndrome, and Ig4-associated cholangitis. Each patient with autoimmune liver disease is different, so it is impossible to accurately determine how long a patient needs to be treated, for example, some patients with Ig4-related cholangitis have been reported to have complete long-term remission with three months of treatment; while patients with autoimmune hepatitis are very likely to have failed to be treated with medication or have a condition of incomplete response, or may even have failed to be treated. In conclusion, many factors can affect the length of treatment for autoimmune liver disease, but regardless of the individual’s condition, he or she should actively cooperate with the doctor to adhere to the treatment.