Autoimmune liver diseases clinically include autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis. All three diseases have different serologic features, and basically all of them present with abnormal liver function, mainly manifested by elevated glutamate transaminase, glutamic oxalacetic transaminase, glutamyl transpeptidase, and alkaline phosphatase. In addition, autoimmune hepatitis also presents with immunoglobulin abnormalities, with elevated globulins and elevated IgG. All 3 diseases present with autoimmune hepatitis antibodies such as anti-gp210, anti-Sp100, anti-mitochondrial antibodies, anti-nuclear antibodies, and positive anti-smooth muscle antibodies. Autoimmune hepatitis is also likely to be complicated by anti-dsDNA, positive anti-CENP antibodies, etc. Especially in autoimmune cholangitis, positive anti-mitochondrial antibody type M2 is a more specific diagnostic marker, but of course there are times when the indicators are not so typical. If autoimmune liver disease is suspected, a liver biopsy can also be done to find out if there are characteristic manifestations such as lymphocytic infiltration, interface hepatitis, and bile duct destruction.