Gout attack can be treated by taking non-steroidal anti-inflammatory drugs (e.g. diclofenac sodium), colchicine, glucocorticosteroids (e.g. prednisone), drugs to promote uric acid excretion (e.g. phenylbromarone) and drugs to inhibit uric acid production (e.g. febuxostat).
1. Non-steroidal anti-inflammatory drugs (NSAIDs): they can inhibit the enzyme cyclo-oxygenase, thus reducing the production of prostaglandins, with anti-inflammatory and analgesic effects, and the common drugs are diclofenac sodium, etoricoxib and so on.
2. Colchicine: It can control joint pain, swelling and other symptoms by inhibiting the chemotaxis of neutrophils and local cell production of interleukins, etc. Common drugs include colchicine.
3. Glucocorticoid drugs: If the treatment of non-steroidal anti-inflammatory drugs and colchicine is ineffective or there are contraindications, patients can take glucocorticoid drugs as prescribed by the doctor, and the common drugs are prednisone, hydrocortisone, dexamethasone and so on.
4. Promote uric acid excretion drugs: can inhibit uric acid reabsorption through renal tubules, increase uric acid excretion, reduce blood uric acid. Commonly used drugs are benzbromarone and probenecid.
5. Inhibition of uric acid synthesis drugs: can inhibit xanthine oxidase, blocking hypoxanthine, xanthine into uric acid, so as to reduce the level of blood uric acid. Commonly used drugs are febuxostat, allopurinol and so on.
It is recommended to go to the regular hospital when gout attack, under the guidance of the doctor to use drugs, strictly prohibit the abuse of drugs, so as not to cause adverse consequences.