Neonatal sputum suction needs to be operated by professional neonatologists, do not operate at home without authorization to avoid danger. The process of neonatal sputum suction operation mainly has the following aspects: First, before suctioning, check whether the suction device is in good performance, and whether each catheter is connected correctly. Second, the baby to take the supine position or lateral position, first suction mucus in the mouth, and then suction mucus nostrils, so as to avoid injecting mucus into the trachea when wheezing or crying. Third, the negative pressure should be moderate, according to the viscosity of mucus, adjusted at 60mmHg-100mmHg, do not insert the suction tube in the process of negative pressure suction. When suctioning, rotate the tube while suctioning and lift it upward, so as not to damage the mucous membrane by continuously adsorbing the tube at one point. The time of each suction is not more than 10 seconds, and the suction tube should not be inserted too deeply to avoid causing vomiting reflex. In the process of sputum suction, pay attention to observe the baby’s color and respiration, if abnormalities are found, sputum suction should be stopped immediately, and then suction again when the situation improves. 6. The liquid reservoir bottle should not be overfilled with suction liquid, and it should be poured out in time. vii. After the operation, record the color, nature and amount of the aspirate.