Medication maintenance therapy for schizophrenia is essential. The type and dose of medication used for maintenance treatment should vary from person to person, primarily based on the patient’s sensitivity to the medication. In some patients, although the dose of medication is high, there are no obvious side effects and the symptoms are well controlled, so there is no need to increase or decrease the dose; in other patients, the dose of medication is not large and the patient can live and work normally after the symptoms disappear, so there is no need to increase the dose. In general, there is no uniform standard for the dose of maintenance drugs. The best method and the most practical way is to individualize the dose. How to choose a drug for maintenance treatment? It can be considered according to the following points: 1, the regular treatment of effective drugs, as they say: effective not more square, there is no doubt about this. 2, as far as possible, a single medication, one is simple and convenient usage, the second patient easy to accept. 3, the combination of drugs can also be chosen, only when a drug does not work well, and the emergence of side effects. But this method is used as little as possible, and must be carried out under the guidance of a doctor. 4, long-acting anti-psychotic drugs are also a good treatment. At present, the cheap drugs available in China are oral pentafluridol tablets, intramuscular fluphenazine decanoate and haloperidol decanoate; the more expensive drugs are intramuscular paliperidone palmitate injection; the choice can be made according to the specific situation. Maintenance treatment should be chosen at a suitable dose, and strive to effectively prevent relapse with minimal side effects, so as to ensure that patients adhere to the dose, but also adapt to the social environment and resume a normal life. Specific implementation methods can be used: 1, low dose, generally 1/2 to 1/4 of the effective therapeutic dose is appropriate; 2, the continuation of the therapeutic dose, some new antipsychotics are not significant side effects, or some patients need higher doses of drugs to maintain treatment; therefore, the therapeutic dose is both the maintenance dose, maintenance treatment does not need to reduce the drug. 3. The most appropriate dose, depending on the individual, should be the drug dose that brings the least side effects and better efficacy to the patient; for patients whose condition has been in remission and stable for several years and who are functioning well socially, the optimal dose can be explored. For patients who have been in remission for several years and have good social function, the optimal dose can be found. As for the duration of maintenance treatment, it should be treated according to different situations: 1. If the symptoms of schizophrenia are relieved after treatment and clinical recovery is achieved, in principle, a certain period of maintenance treatment should be adhered to; 2. If the initial onset of schizophrenia is treated promptly and the condition recovers well, coupled with good work and family environment support, and the patient is able to cope with various mental stresses and internal conflicts, and rehabilitation measures are also effective, it is still After 2 years of maintenance treatment, try to reduce or stop the drug under the guidance of the doctor. 3. If the symptoms are typical, the dosage of treatment is large, the recovery is unsatisfactory, and the rehabilitation measures are not perfect, the maintenance period should be longer, up to 4-5 years; 4. If the patient’s condition is unstable for a long time, or there are multiple relapses, it is better to insist on long-term maintenance treatment.