Weakness of hands and feet after gout injection may be caused by lack of nutrients, or it may be caused by the use of hypokalemia, and it is recommended to be diagnosed and treated reasonably under the guidance of a doctor. Gout patients may experience weakness of hands and feet after injection due to some nutrient deficiencies such as hypokalemia after a light, low purine diet. In this case, the missing nutrients can be supplemented appropriately, such as proper consumption of high-sugar food when hypoglycemia, and intravenous glucose supplementation if necessary, to help patients recover nutrition and physical strength. In addition, gout patients in the treatment of glucocorticoid hormones such as methylprednisolone, etc., such drugs may cause potassiumemia, patients will also show symptoms such as limb weakness, anorexia, nausea and so on. At this time, potassium should be immediately supplemented in the patient’s body through oral or intravenous to relieve the symptoms. In case of weakness of arms and legs after gout injection, patients are advised to seek immediate medical attention and be seen as soon as possible under the guidance of a doctor.