Sputum from a cold may be an upper respiratory tract infection accompanied by a lower respiratory tract infection. In case of the above clinical manifestations, expectorant medications such as aminoglutethimide, eucalyptus citrulline, and acetylcysteine may be used. At the same time, it is important to actively seek medical attention to improve the blood routine, C-reactive protein, mycoplasma antibodies and other related tests to assess the possible causative organisms of the infection and make targeted treatment. When the infection is viral, antipyretic and detoxifying drugs can be used, such as Four Seasons Cold and Flu Capsules, Qing Kai Ling, Pu Di Lan, Ban Lan Gen, etc. Antiviral drugs, such as Oseltamivir and Abidor, can also be used. When patients are bacterial infections, they can be treated with antibiotics, commonly used antibiotics include cefixime, amoxicillin, etc. If the patient has a combination of infections with atypical pathogenic bacteria, azithromycin and levofloxacin may be used.