Swelling and stiffness of hands may be related to rheumatoid arthritis, poor blood circulation and other factors, and can be treated with medication under the guidance of a doctor. 1. Rheumatoid arthritis: Rheumatoid arthritis is usually caused by the environment, lowered immunity, heredity and other factors, and is accompanied by swelling, stiffness, pain and other discomforts in the joints of both hands. Medicines such as methotrexate and hydroxychloroquine can be used under the guidance of doctors to relieve it. 2. Poor blood circulation: mainly due to the patient’s long time working with both hands, or cold caused by the tendon and joint capsule repeated pulling, thus appearing hands strain, poor blood circulation phenomenon, usually manifested as hands swelling, hardness and other phenomena. Patients can use hot towels to apply hot compresses to the local area, and the symptoms can be relieved after appropriate rest. If the symptoms of swelling and stiffness of both hands persist, they should go to the hospital in time for consultation and treatment.