Taking general cold medicines on the 40th day of pregnancy will not cause fetal malformations, and the incidence of fetal malformations is not significantly different from that of the normal population generally around 1%-2%. Most cold medicines can be taken during pregnancy, including Tylenol cold tablets, Tylenol and so on, and some traditional Chinese cold medicines such as Banlangen, cold and clear heat granules can also be taken during pregnancy. These medications do not increase the rate of fetal malformations. If a cold is combined with an infection, antibiotics should be given. Cephalosporin antibiotics such as Ciclosporin or azithromycin are safe to use during pregnancy, while quinolone antibiotics such as colestipol or tetracycline antibiotics are prohibited during pregnancy.