The research progress of Chinese medicine treatment of ulcerative colitis Sun Zhen, Department of Traditional Chinese Medicine, Tangshan Branch, Nanjing General Hospital, Nanjing Military Region Ulcerative colitis (UC), also known as chronic nonspecific ulcerative colitis, is an inflammatory lesion with an undefined etiology that mainly invades the mucosa and submucosa of the large intestine (rectum and colon). Clinically, the disease is characterized by diarrhea, abdominal pain, mucopurulent stools, and severe local (intestinal tract itself) and distant complications, and in a few cases, fulminant onset, which can be critical and even life-threatening. The disease was first considered to be a separate disease from bacillary dysentery and was first described by Samuel Wilks at Guy’s Hospital in London, England, in 1859, when he noted that it was a form of colitis different from congestion, mercury poisoning, diphtheria inflammation, and ulcers due to bacillary dysentery. The disease was first reported in China in 1959, and in recent years there has been a marked increase in this disease. The acute fulminant mortality of the disease is high, while the chronic recurrent type is prone to cancer, and the average incidence of cancer is reported to be 3.5%-7%, which is 5-10 times higher than that of the normal population. Due to the increase in the number of patients with this disease, it is difficult to cure, easy to recur, persistent, and is related to the development of colon cancer, and is listed by the World Health Organization as one of the difficult to treat diseases in modern medicine, and has been widely valued by domestic and foreign academics, and has become a hot spot for research on Chinese and Western medicine digestive diseases in recent years. The ancient books of Chinese medicine do not have the name of ulcerative colitis, but the understanding of its pathology has been discussed by many doctors in the past generations. The material is like snot and pus, sticky, slippery and greasy, and when it is discharged, it is not easy to get rid of it. The Chinese medicine believes that the occurrence of this disease is related to the deficiency of spleen qi due to the six evil spirits, internal injury of emotions, poor diet, irregular living and the lack of innate endowment, many factors lead to spleen qi damage, loss of transport and transformation, water and grain do not transform the essence, dampness and turbidity, down to the intestines, for drainage for dysentery; dampness and heat, Qi and blood stagnation, stagnation of intestinal tract, meat and blood The dysentery is red and white; the abdominal pain is caused by blockage of qi and the internal Qi. Chinese medicine believes that the disease is mainly in the large intestine, closely related to the spleen and stomach, and affects and involves the liver and kidney. The pathogenesis of the disease always belongs to the original deficiency and the symptoms of the disease, spleen deficiency for this, the disease can involve the kidney, resulting in the deficiency of both spleen and kidney, and the combination of dampness, heat and toxicity, stasis of blood and the symptoms of the disease. Chinese medicine treats this disease from “dysentery”, “intestinal urticaria”, and “intestinal nettle-sense gullies”. The treatment is based on the principle of supporting the righteousness and eliminating the evil or both, and the methods include internal administration of Chinese medicine, local enema and the combination of both.